diff --git a/CHANGELOG.md b/CHANGELOG.md
index 644ffba7..2e4bb433 100644
--- a/CHANGELOG.md
+++ b/CHANGELOG.md
@@ -88,6 +88,7 @@ removed on this schedule:
 - Fix `headscale users destroy`/`rename` reporting "multiple users match query" when no user matches; an ambiguous match now lists the matching users [#3476](https://github.com/juanfont/headscale/pull/3476)
 - Deleting a user that still owns nodes now lists the nodes (ID and hostname) that must be deleted first [#3475](https://github.com/juanfont/headscale/pull/3475)
 - Headscale now requires Go 1.27 to build
+- A `derp.paths` region set to `null` removes that region again, as documented
 
 ## 0.29.4 (2026-09-23)
 
diff --git a/hscontrol/derp/derp.go b/hscontrol/derp/derp.go
index c7c2c5ad..03b67171 100644
--- a/hscontrol/derp/derp.go
+++ b/hscontrol/derp/derp.go
@@ -82,9 +82,14 @@ func mergeDERPMaps(derpMaps []*tailcfg.DERPMap) *tailcfg.DERPMap {
 		// shuffle alias regions shared with the source map or a previously
 		// served map, racing concurrent readers.
 		for id, region := range derpMap.Regions {
-			if cloned := region.Clone(); cloned != nil {
-				result.Regions[id] = cloned
+			// A null region removes one an earlier map added, the documented
+			// way to drop a region from derp.urls via derp.paths.
+			if region == nil {
+				delete(result.Regions, id)
+				continue
 			}
+
+			result.Regions[id] = region.Clone()
 		}
 	}
 
diff --git a/hscontrol/derp/derp_merge_test.go b/hscontrol/derp/derp_merge_test.go
index 330bcf59..804c7f7a 100644
--- a/hscontrol/derp/derp_merge_test.go
+++ b/hscontrol/derp/derp_merge_test.go
@@ -26,3 +26,20 @@ func TestMergeDERPMapsClonesRegions(t *testing.T) {
 	assert.Equal(t, "a", src.Regions[1].Nodes[0].Name,
 		"source region was mutated through a shared pointer")
 }
+
+// TestMergeDERPMapsNullRemovesRegion pins docs/ref/derp.md's recipe: a later
+// map setting a region to null drops it from the result.
+func TestMergeDERPMapsNullRemovesRegion(t *testing.T) {
+	base := &tailcfg.DERPMap{
+		Regions: map[tailcfg.DERPRegionID]*tailcfg.DERPRegion{
+			1: {RegionID: 1, RegionCode: "nyc"},
+			2: {RegionID: 2, RegionCode: "sfo"},
+		},
+	}
+	drop := &tailcfg.DERPMap{Regions: map[tailcfg.DERPRegionID]*tailcfg.DERPRegion{1: nil}}
+
+	merged := mergeDERPMaps([]*tailcfg.DERPMap{base, drop})
+
+	assert.NotContains(t, merged.Regions, tailcfg.DERPRegionID(1))
+	assert.Contains(t, merged.Regions, tailcfg.DERPRegionID(2))
+}